Does breast carcinoma belong to the Lynch syndrome tumor spectrum? – Somatic mutational profiles vs. ovarian and colorectal carcinomas

Inherited DNA mismatch repair (MMR) defects cause predisposition to colorectal, endometrial, ovarian, and other cancers occurring in Lynch syndrome (LS). It is unsettled whether breast carcinoma belongs to the LS tumor spectrum. We approached this question through somatic mutational analysis of brea...

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Detalles Bibliográficos
Autores principales: Porkka, Noora K., Olkinuora, Alisa, Kuopio, Teijo, Ahtiainen, Maarit, Eldfors, Samuli, Almusa, Henrikki, Mecklin, Jukka-Pekka, Peltomäki, Päivi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147090/
https://www.ncbi.nlm.nih.gov/pubmed/32292574
http://dx.doi.org/10.18632/oncotarget.27538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147090/
https://www.ncbi.nlm.nih.gov/pubmed/32292574
http://dx.doi.org/10.18632/oncotarget.27538

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