Adenoviral protein E4orf4 interacts with the polarity protein Par3 to induce nuclear rupture and tumor cell death

The tumor cell–selective killing activity of the adenovirus type 2 early region 4 ORF4 (E4orf4) protein is poorly defined at the molecular level. Here, we show that the tumoricidal effect of E4orf4 is typified by changes in nuclear dynamics that depend on its interaction with the polarity protein Pa...

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Detalles Bibliográficos
Autores principales: Dziengelewski, Claire, Rodrigue, Marc-Antoine, Caillier, Alexia, Jacquet, Kévin, Boulanger, Marie-Chloé, Bergeman, Jonathan, Fuchs, Margit, Lambert, Herman, Laprise, Patrick, Richard, Darren E., Bordeleau, François, Huot, Marc-Étienne, Lavoie, Josée N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147092/
https://www.ncbi.nlm.nih.gov/pubmed/32328642
http://dx.doi.org/10.1083/jcb.201805122

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147092/
https://www.ncbi.nlm.nih.gov/pubmed/32328642
http://dx.doi.org/10.1083/jcb.201805122

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