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Spectrin couples cell shape, cortical tension, and Hippo signaling in retinal epithelial morphogenesis
Although extracellular force has a profound effect on cell shape, cytoskeleton tension, and cell proliferation through the Hippo signaling effector Yki/YAP/TAZ, how intracellular force regulates these processes remains poorly understood. Here, we report an essential role for spectrin in specifying c...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147103/ https://www.ncbi.nlm.nih.gov/pubmed/32328630 http://dx.doi.org/10.1083/jcb.201907018 |