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Spectrin couples cell shape, cortical tension, and Hippo signaling in retinal epithelial morphogenesis

Although extracellular force has a profound effect on cell shape, cytoskeleton tension, and cell proliferation through the Hippo signaling effector Yki/YAP/TAZ, how intracellular force regulates these processes remains poorly understood. Here, we report an essential role for spectrin in specifying c...

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Detalles Bibliográficos
Autores principales: Deng, Hua, Yang, Limin, Wen, Pei, Lei, Huiyan, Blount, Paul, Pan, Duojia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147103/
https://www.ncbi.nlm.nih.gov/pubmed/32328630
http://dx.doi.org/10.1083/jcb.201907018