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Asymmetric assembly of centromeres epigenetically regulates stem cell fate

Centromeres are epigenetically defined by CENP-A–containing chromatin and are essential for cell division. Previous studies suggest asymmetric inheritance of centromeric proteins upon stem cell division; however, the mechanism and implications of selective chromosome segregation remain unexplored. W...

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Detalles Bibliográficos
Autores principales: Dattoli, Anna Ada, Carty, Ben L., Kochendoerfer, Antje M., Morgan, Conall, Walshe, Annie E., Dunleavy, Elaine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147107/
https://www.ncbi.nlm.nih.gov/pubmed/32328637
http://dx.doi.org/10.1083/jcb.201910084