Cargando…
Asymmetric assembly of centromeres epigenetically regulates stem cell fate
Centromeres are epigenetically defined by CENP-A–containing chromatin and are essential for cell division. Previous studies suggest asymmetric inheritance of centromeric proteins upon stem cell division; however, the mechanism and implications of selective chromosome segregation remain unexplored. W...
Autores principales: | Dattoli, Anna Ada, Carty, Ben L., Kochendoerfer, Antje M., Morgan, Conall, Walshe, Annie E., Dunleavy, Elaine M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147107/ https://www.ncbi.nlm.nih.gov/pubmed/32328637 http://dx.doi.org/10.1083/jcb.201910084 |
Ejemplares similares
-
Centromere function in asymmetric cell division in Drosophila female and male germline stem cells
por: Kochendoerfer, Antje M., et al.
Publicado: (2021) -
CENP-C functions in centromere assembly, the maintenance of CENP-A asymmetry and epigenetic age in Drosophila germline stem cells
por: Carty, Ben L., et al.
Publicado: (2021) -
Centromere proteins are asymmetrically distributed between newly divided germline stem and daughter cells and maintain a balanced niche in Drosophila males
por: Kochendoerfer, Antje M., et al.
Publicado: (2023) -
Truly epigenetic: A centromere finds a “neo” home
por: Carty, Ben L., et al.
Publicado: (2021) -
Nucleolar activity and CENP-C regulate CENP-A and CAL1 availability for centromere assembly in meiosis
por: Kwenda, Lucretia, et al.
Publicado: (2016)