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Fission and fusion machineries converge at ER contact sites to regulate mitochondrial morphology

The steady-state morphology of the mitochondrial network is maintained by a balance of constitutive fission and fusion reactions. Disruption of this steady-state morphology results in either a fragmented or elongated network, both of which are associated with altered metabolic states and disease. Ho...

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Detalles Bibliográficos
Autores principales: Abrisch, Robert G., Gumbin, Samantha C., Wisniewski, Brett Taylor, Lackner, Laura L., Voeltz, Gia K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147108/
https://www.ncbi.nlm.nih.gov/pubmed/32328629
http://dx.doi.org/10.1083/jcb.201911122