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Fission and fusion machineries converge at ER contact sites to regulate mitochondrial morphology
The steady-state morphology of the mitochondrial network is maintained by a balance of constitutive fission and fusion reactions. Disruption of this steady-state morphology results in either a fragmented or elongated network, both of which are associated with altered metabolic states and disease. Ho...
Autores principales: | Abrisch, Robert G., Gumbin, Samantha C., Wisniewski, Brett Taylor, Lackner, Laura L., Voeltz, Gia K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147108/ https://www.ncbi.nlm.nih.gov/pubmed/32328629 http://dx.doi.org/10.1083/jcb.201911122 |
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