Cross-sectional and longitudinal measures of chitinase proteins in amyotrophic lateral sclerosis and expression of CHI3L1 in activated astrocytes

OBJECTIVE: Amyotrophic lateral sclerosis (ALS) is a complex disease with numerous pathological mechanisms resulting in a heterogeneous patient population. Using biomarkers for particular disease mechanisms may enrich a homogeneous subset of patients. In this study, we quantified chitotriosidase (Chi...

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Detalles Bibliográficos
Autores principales: Vu, Lucas, An, Jiyan, Kovalik, Tina, Gendron, Tania, Petrucelli, Leonard, Bowser, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2020
Materias:
Neuro-Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147184/
https://www.ncbi.nlm.nih.gov/pubmed/31937582
http://dx.doi.org/10.1136/jnnp-2019-321916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147184/
https://www.ncbi.nlm.nih.gov/pubmed/31937582
http://dx.doi.org/10.1136/jnnp-2019-321916

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