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Neutrophil L-Plastin Controls Ocular Paucibacteriality and Susceptibility to Keratitis

Why ocular mucosa is paucibacterial is unknown. Many different mechanisms have been suggested but the comprehensive experimental studies are sparse. We found that a deficiency in L-plastin (LCP1), an actin bundling protein, resulted in an ocular commensal overgrowth, characterized with increased pre...

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Detalles Bibliográficos
Autores principales: Lu, Xiaoxiao, Kugadas, Abirami, Smith-Page, Kirsten, Lamb, Jeffrey, Lin, Tiffany, Ru, Yusha, Morley, Sharon Celeste, Fichorova, Raina, Mittal, Sharad K., Chauhan, Sunil K., Littleton, Sejiro, Saban, Daniel, Gadjeva, Mihaela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147296/
https://www.ncbi.nlm.nih.gov/pubmed/32318063
http://dx.doi.org/10.3389/fimmu.2020.00547