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Neutrophil L-Plastin Controls Ocular Paucibacteriality and Susceptibility to Keratitis
Why ocular mucosa is paucibacterial is unknown. Many different mechanisms have been suggested but the comprehensive experimental studies are sparse. We found that a deficiency in L-plastin (LCP1), an actin bundling protein, resulted in an ocular commensal overgrowth, characterized with increased pre...
Autores principales: | Lu, Xiaoxiao, Kugadas, Abirami, Smith-Page, Kirsten, Lamb, Jeffrey, Lin, Tiffany, Ru, Yusha, Morley, Sharon Celeste, Fichorova, Raina, Mittal, Sharad K., Chauhan, Sunil K., Littleton, Sejiro, Saban, Daniel, Gadjeva, Mihaela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147296/ https://www.ncbi.nlm.nih.gov/pubmed/32318063 http://dx.doi.org/10.3389/fimmu.2020.00547 |
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