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Astragaloside IV Exerts Cognitive Benefits and Promotes Hippocampal Neurogenesis in Stroke Mice by Downregulating Interleukin-17 Expression via Wnt Pathway

BACKGROUND: Stroke remains a leading cause of adult disability and the demand for stroke rehabilitation services is growing, and Astragaloside IV (As IV), a primary bioactive compound of Radix Astragali : Astragalus mongholicus Bunge (Fabaceae), may be a promising stroke therapy. METHODS: To access...

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Detalles Bibliográficos
Autores principales: Sun, Li, Zhang, Heming, Wang, Wen, Chen, Zhiyang, Wang, Shuang, Li, Jiangjing, Li, Guangyao, Gao, Changjun, Sun, Xude
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147333/
https://www.ncbi.nlm.nih.gov/pubmed/32317974
http://dx.doi.org/10.3389/fphar.2020.00421