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Native LESA TWIMS-MSI: Spatial, Conformational, and Mass Analysis of Proteins and Protein Complexes

[Image: see text] We have previously demonstrated native liquid extraction surface analysis (LESA) mass spectrometry imaging of small intact proteins in thin tissue sections. We also showed calculation of collision cross sections for specific proteins extracted from discrete locations in tissue by L...

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Detalles Bibliográficos
Autores principales: Hale, Oliver J., Sisley, Emma K., Griffiths, Rian L., Styles, Iain B., Cooper, Helen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147347/
https://www.ncbi.nlm.nih.gov/pubmed/32159346
http://dx.doi.org/10.1021/jasms.9b00122