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A novel bis-aryl urea compound inhibits tumor proliferation via cathepsin D-associated apoptosis

Derivatives of bis-aryl urea have been widely investigated for their various biological activities, such as antiviral, anti-inflammatory and antiproliferative. We evaluated a new chemical entity consisting of bis-aryl urea moiety, N69B, for its anticancer activities and explored their underlying mol...

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Detalles Bibliográficos
Autores principales: Wu, Jianping, Huang, Yao, Xie, Qian, Zhang, Junfeng, Zhan, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147394/
https://www.ncbi.nlm.nih.gov/pubmed/31917700
http://dx.doi.org/10.1097/CAD.0000000000000898