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MsrA Suppresses Inflammatory Activation of Microglia and Oxidative Stress to Prevent Demyelination via Inhibition of the NOX2-MAPKs/NF-κB Signaling Pathway

INTRODUCTION: Demyelination causes neurological deficits involving visual, motor, sensory symptoms. Deregulation of several enzymes has been identified in demyelination, which holds potential for the development of treatment strategies for demyelination. However, the specific effect of methionine su...

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Detalles Bibliográficos
Autores principales: Fan, Hua, Li, Damiao, Guan, Xinlei, Yang, Yanhui, Yan, Junqiang, Shi, Jian, Ma, Ranran, Shu, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147623/
https://www.ncbi.nlm.nih.gov/pubmed/32308370
http://dx.doi.org/10.2147/DDDT.S223218