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Micro-vesicles from mesenchymal stem cells over-expressing miR-34a inhibit transforming growth factor-β1-induced epithelial-mesenchymal transition in renal tubular epithelial cells in vitro

BACKGROUND: The use of microRNAs in the therapy of kidney disease is hampered by the difficulties in their effective delivery. Micro-vesicles (MVs) are known as natural carriers of small RNAs. Our prior research has demonstrated that MVs isolated from mesenchymal stem cells (MSCs) are capable of att...

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Detalles Bibliográficos
Autores principales: He, Juan, Jiang, Ya-Li, Wang, Yan, Tian, Xiu-Juan, Sun, Shi-Ren
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147664/
https://www.ncbi.nlm.nih.gov/pubmed/32149762
http://dx.doi.org/10.1097/CM9.0000000000000720