Ataxic Symptoms in Huntington’s Disease Transgenic Mouse Model Are Alleviated by Chlorzoxazone

Huntington’s disease (HD) is a hereditary neurodegenerative disease caused by a polyglutamine expansion in the huntingtin protein, Striatum atrophy in HD leads to a progressive disturbance of psychiatric, motor, and cognitive function. Recent studies of HD patients revealed that the degeneration of...

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Detalles Bibliográficos
Autores principales: Egorova, Polina A., Gavrilova, Aleksandra V., Bezprozvanny, Ilya B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147686/
https://www.ncbi.nlm.nih.gov/pubmed/32317916
http://dx.doi.org/10.3389/fnins.2020.00279

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147686/
https://www.ncbi.nlm.nih.gov/pubmed/32317916
http://dx.doi.org/10.3389/fnins.2020.00279

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