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High-mobility group box 1 fragment suppresses adverse post-infarction remodeling by recruiting PDGFRα-positive bone marrow cells

OBJECTIVES: High-mobility group box 1 protein (HMGB1) fragment enhances bone marrow-derived mesenchymal stem cell (BM-MSC) recruitment to damaged tissue to promote tissue regeneration. This study aimed to evaluate whether systemic injection of HMGB1 fragment could promote tissue repair in a rat mode...

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Detalles Bibliográficos
Autores principales: Goto, Takasumi, Miyagawa, Shigeru, Tamai, Katsuto, Matsuura, Ryohei, Kido, Takashi, Kuratani, Toru, Shimamura, Kazuo, Sakaniwa, Ryoto, Harada, Akima, Sawa, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147742/
https://www.ncbi.nlm.nih.gov/pubmed/32275672
http://dx.doi.org/10.1371/journal.pone.0230392