Select autophagy genes maintain quiescence of tissue-resident macrophages and increase susceptibility to Listeria monocytogenes

Innate and adaptive immune responses that prime myeloid cells, such as macrophages, protect against pathogens(1,2). However, if left uncontrolled, these responses may lead to detrimental inflammation(3). Thus macrophages, particularly those resident in tissues, must remain quiescent in between infec...

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Detalles Bibliográficos
Autores principales: Wang, Ya-Ting, Zaitsev, Konstantin, Lu, Qun, Li, Shan, Schaiff, W. Timothy, Kim, Ki-Wook, Droit, Lindsay, Wilen, Craig B., Desai, Chandni, Balce, Dale R., Orchard, Robert C., Orvedahl, Anthony, Park, Sunmin, Kreamalmeyer, Darren, Handley, Scott A., Pfeifer, John D., Baldridge, Megan T., Artyomov, Maxim N., Stallings, Christina L, Virgin, Herbert W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147835/
https://www.ncbi.nlm.nih.gov/pubmed/31959973
http://dx.doi.org/10.1038/s41564-019-0633-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147835/
https://www.ncbi.nlm.nih.gov/pubmed/31959973
http://dx.doi.org/10.1038/s41564-019-0633-0

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