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Identification of a Mimotope Peptide Bound to the SARS-CoV Spike Protein Specific Monoclonal Antibody 2C5 with Phage-displayed Peptide Library

This article aims to identify the epitope corresponding to SARS-CoV spike protein specific neutralizing monoclonal antibody (MAb) 2C5. The antibody was used as the target and three rounds of bio-panning were conducted with a phage-displayed peptide library. After the third panning, 20 phage-plaque c...

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Detalles Bibliográficos
Autores principales: HUA, Rong-Hong, WU, Dong-Lai, TONG, Guang-Zhi, WANG, Yun-Feng, TIAN, Zhi-Jun, ZHOU, Yan-Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Institute of Microbiology, Chinese Academy of Sciences and Chinese Society for Microbiology. Published by Elsevier B.V. 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147893/
https://www.ncbi.nlm.nih.gov/pubmed/17037189
http://dx.doi.org/10.1016/S1872-2075(06)60051-4