Transformable peptide nanoparticles arrest HER2 signalling and cause cancer cell death in vivo

Human epidermal growth factor receptor 2 (HER2) is overexpressed in over 20% of breast cancers. The dimerization of HER2 receptors leads to the activation of down-stream signals enabling proliferation and survival of malignant phenotypes. Owing to the high expression levels of HER2, combination ther...

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Detalles Bibliográficos
Autores principales: Zhang, Lu, Jing, Di, Jiang, Nian, Rojalin, Tatu, Baehr, Christopher Michael, Zhang, Dalin, Xiao, Wenwu, Wu, Yi, Cong, Zhaoqing, Li, Jian Jian, Li, Yuanpei, Wang, Lei, Lam, Kit S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147967/
https://www.ncbi.nlm.nih.gov/pubmed/31988501
http://dx.doi.org/10.1038/s41565-019-0626-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7147967/
https://www.ncbi.nlm.nih.gov/pubmed/31988501
http://dx.doi.org/10.1038/s41565-019-0626-4

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