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Does Intensive Treatment Select for Praziquantel Resistance in High-Transmission Settings? Parasitological Trends and Treatment Efficacy Within a Cluster-Randomized Trial

BACKGROUND: Praziquantel mass drug administration (MDA) is recommended in schistosomiasis-endemic areas. Animal models demonstrate Schistosoma parasite resistance to praziquantel after repeated exposure. METHODS: We conducted a parasitological survey in 26 fishing communities in Uganda after 4 years...

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Detalles Bibliográficos
Autores principales: Tushabe, John Vianney, Lubyayi, Lawrence, Sserubanja, Joel, Kabuubi, Prossy, Abayo, Elson, Kiwanuka, Samuel, Nassuuna, Jacent, Kaweesa, James, Corstjens, Paul, van Dam, Govert, Sanya, Richard E, Ssenyonga, William, Tukahebwa, Edridah Muheki, Kabatereine, Narcis B, Elliott, Alison M, Webb, Emily L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148002/
https://www.ncbi.nlm.nih.gov/pubmed/32296727
http://dx.doi.org/10.1093/ofid/ofaa091