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Does Intensive Treatment Select for Praziquantel Resistance in High-Transmission Settings? Parasitological Trends and Treatment Efficacy Within a Cluster-Randomized Trial
BACKGROUND: Praziquantel mass drug administration (MDA) is recommended in schistosomiasis-endemic areas. Animal models demonstrate Schistosoma parasite resistance to praziquantel after repeated exposure. METHODS: We conducted a parasitological survey in 26 fishing communities in Uganda after 4 years...
Autores principales: | Tushabe, John Vianney, Lubyayi, Lawrence, Sserubanja, Joel, Kabuubi, Prossy, Abayo, Elson, Kiwanuka, Samuel, Nassuuna, Jacent, Kaweesa, James, Corstjens, Paul, van Dam, Govert, Sanya, Richard E, Ssenyonga, William, Tukahebwa, Edridah Muheki, Kabatereine, Narcis B, Elliott, Alison M, Webb, Emily L |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148002/ https://www.ncbi.nlm.nih.gov/pubmed/32296727 http://dx.doi.org/10.1093/ofid/ofaa091 |
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