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Systematic identification of silencers in human cells

The majority of the human genome does not encode proteins. Many of these noncoding regions contain important regulatory sequences that control gene expression. To date, most studies have focused on activators such as enhancers, but regions that repress gene expression—silencers—have not been systema...

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Detalles Bibliográficos
Autores principales: Pang, Baoxu, Snyder, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148122/
https://www.ncbi.nlm.nih.gov/pubmed/32094911
http://dx.doi.org/10.1038/s41588-020-0578-5