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Long Noncoding RNA SOCS2-AS Promotes Leukemogenesis in FLT3-ITD+ Acute Myeloid Leukemia Through miRNA-221

BACKGROUND: LncRNAs play an important role in tumorigenesis and development in tumors, but the function of lncRNA SOCS2-AS in acute myeloid leukemia (AML) is unknown. MATERIALS AND METHODS: In the present study, we used RT-PCR to detect the expression of SOCS2-AS in FLT3-ITD+, FLT3-ITD- AML patients...

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Detalles Bibliográficos
Autores principales: Zhang, Rong, Huo, Cai-hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148164/
https://www.ncbi.nlm.nih.gov/pubmed/32308425
http://dx.doi.org/10.2147/OTT.S222734