Copper-Mediated Synthesis of Drug-like Bicyclopentanes

Multicomponent reactions (MCRs) have become a mainstay in both academic and industrial synthetic organic chemistry due to their step- and atom-economy advantages over traditional synthetic sequences(1). Recently, bicyclo[1.1.1]pentane (BCP) motifs have come to the fore as valuable pharmaceutical bio...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Xiaheng, Smith, Russell T., Le, Chip, McCarver, Stefan J., Shireman, Brock T., Carruthers, Nicholas I., MacMillan, David W. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148169/
https://www.ncbi.nlm.nih.gov/pubmed/32066140
http://dx.doi.org/10.1038/s41586-020-2060-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148169/
https://www.ncbi.nlm.nih.gov/pubmed/32066140
http://dx.doi.org/10.1038/s41586-020-2060-z

Ejemplares similares