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Intermittent exposure to whole cigarette smoke alters the differentiation of primary small airway epithelial cells in the air-liquid interface culture

Cigarette smoke (CS) is the leading risk factor to develop COPD. Therefore, the pathologic effects of whole CS on the differentiation of primary small airway epithelial cells (SAEC) were investigated, using cells from three healthy donors and three COPD patients, cultured under ALI (air-liquid inter...

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Detalles Bibliográficos
Autores principales: Gindele, Julia A., Kiechle, Tobias, Benediktus, Kerstin, Birk, Gerald, Brendel, Michael, Heinemann, Fabian, Wohnhaas, Christian T., LeBlanc, Michelle, Zhang, Haijun, Strulovici-Barel, Yael, Crystal, Ronald G., Thomas, Matthew J., Stierstorfer, Birgit, Quast, Karsten, Schymeinsky, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148343/
https://www.ncbi.nlm.nih.gov/pubmed/32277131
http://dx.doi.org/10.1038/s41598-020-63345-5