Studies of structural determinants of substrate binding in the Creatine Transporter (CreaT, SLC6A8) using molecular models

Creatine is a crucial metabolite that plays a fundamental role in ATP homeostasis in tissues with high-energy demands. The creatine transporter (CreaT, SLC6A8) belongs to the solute carrier 6 (SLC6) transporters family, and more particularly to the GABA transporters (GATs) subfamily. Understanding t...

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Detalles Bibliográficos
Autores principales: Colas, Claire, Banci, Giulia, Martini, Riccardo, Ecker, Gerhard F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148354/
https://www.ncbi.nlm.nih.gov/pubmed/32277128
http://dx.doi.org/10.1038/s41598-020-63189-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148354/
https://www.ncbi.nlm.nih.gov/pubmed/32277128
http://dx.doi.org/10.1038/s41598-020-63189-z

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