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Studies of structural determinants of substrate binding in the Creatine Transporter (CreaT, SLC6A8) using molecular models
Creatine is a crucial metabolite that plays a fundamental role in ATP homeostasis in tissues with high-energy demands. The creatine transporter (CreaT, SLC6A8) belongs to the solute carrier 6 (SLC6) transporters family, and more particularly to the GABA transporters (GATs) subfamily. Understanding t...
Autores principales: | Colas, Claire, Banci, Giulia, Martini, Riccardo, Ecker, Gerhard F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148354/ https://www.ncbi.nlm.nih.gov/pubmed/32277128 http://dx.doi.org/10.1038/s41598-020-63189-z |
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