Directed evolution of a transcription factor PbrR to improve lead selectivity and reduce zinc interference through dual selection

Directed evolution has been proven as a powerful tool for developing proteins and strains with novel or enhanced features. In this study, a dual selection system was designed to tune the binding specificity of a transcription factor to a particular ligand with the ampicillin resistance gene amp (ON...

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Detalles Bibliográficos
Autores principales: Jia, Xiaoqiang, Ma, Yubing, Bu, Rongrong, Zhao, Tingting, Wu, Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148400/
https://www.ncbi.nlm.nih.gov/pubmed/32277291
http://dx.doi.org/10.1186/s13568-020-01004-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148400/
https://www.ncbi.nlm.nih.gov/pubmed/32277291
http://dx.doi.org/10.1186/s13568-020-01004-8

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