ACE-domain selectivity extends beyond direct interacting residues at the active site

Angiotensin-converting enzyme (ACE) is best known for its formation of the vasopressor angiotensin II that controls blood pressure but is also involved in other physiological functions through the hydrolysis of a variety of peptide substrates. The enzyme contains two catalytic domains (nACE and cACE...

Descripción completa

Detalles Bibliográficos
Autores principales: Cozier, Gyles E., Lubbe, Lizelle, Sturrock, Edward D., Acharya, K. Ravi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2020
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148434/
https://www.ncbi.nlm.nih.gov/pubmed/32195541
http://dx.doi.org/10.1042/BCJ20200060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148434/
https://www.ncbi.nlm.nih.gov/pubmed/32195541
http://dx.doi.org/10.1042/BCJ20200060

Ejemplares similares