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ACE-domain selectivity extends beyond direct interacting residues at the active site

Angiotensin-converting enzyme (ACE) is best known for its formation of the vasopressor angiotensin II that controls blood pressure but is also involved in other physiological functions through the hydrolysis of a variety of peptide substrates. The enzyme contains two catalytic domains (nACE and cACE...

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Detalles Bibliográficos
Autores principales:	Cozier, Gyles E., Lubbe, Lizelle, Sturrock, Edward D., Acharya, K. Ravi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Portland Press Ltd. 2020
Materias:	Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148434/ https://www.ncbi.nlm.nih.gov/pubmed/32195541 http://dx.doi.org/10.1042/BCJ20200060

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