Reversal of Hyperglycemia and Suppression of Type 1 Diabetes in the NOD Mouse with Apoptotic DNA Immunotherapy™ (ADi™), ADi-100

The antigen-specific apoptotic DNA immunotherapeutic, ADi-100, is designed to suppress type 1 diabetes and consists of two DNA plasmids encoding genetic sequences of the apoptosis-inducing molecule, BAX, and the secreted form of the autoantigen, glutamic acid decarboxylase 65, that is CpG hyper-meth...

Descripción completa

Detalles Bibliográficos
Autores principales: Alleva, David G., Rezaee, Melika, Yip, Linda, Ren, Gang, Rosenberg, Jarrett, Concepcion, Waldo, Escher, Alan, Shabahang, Shahrokh, Thakor, Avnesh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148463/
https://www.ncbi.nlm.nih.gov/pubmed/32143316
http://dx.doi.org/10.3390/biomedicines8030053

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148463/
https://www.ncbi.nlm.nih.gov/pubmed/32143316
http://dx.doi.org/10.3390/biomedicines8030053

Ejemplares similares