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Transcriptional suppression of AMPKα1 promotes breast cancer metastasis upon oncogene activation
AMP-activated protein kinase (AMPK) functions as an energy sensor and is pivotal in maintaining cellular metabolic homeostasis. Numerous studies have shown that down-regulation of AMPK kinase activity or protein stability not only lead to abnormality of metabolism but also contribute to tumor develo...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148563/ https://www.ncbi.nlm.nih.gov/pubmed/32193335 http://dx.doi.org/10.1073/pnas.1914786117 |