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Transcriptional suppression of AMPKα1 promotes breast cancer metastasis upon oncogene activation

AMP-activated protein kinase (AMPK) functions as an energy sensor and is pivotal in maintaining cellular metabolic homeostasis. Numerous studies have shown that down-regulation of AMPK kinase activity or protein stability not only lead to abnormality of metabolism but also contribute to tumor develo...

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Detalles Bibliográficos
Autores principales: Yi, Yong, Chen, Deshi, Ao, Juan, Zhang, Wenhua, Yi, Jianqiao, Ren, Xiaokun, Fei, Junjie, Li, Fengtian, Niu, Mengmeng, Chen, Hu, Luo, Yangkun, Luo, Zhijun, Xiao, Zhi-Xiong Jim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148563/
https://www.ncbi.nlm.nih.gov/pubmed/32193335
http://dx.doi.org/10.1073/pnas.1914786117