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Specific subfamilies of transposable elements contribute to different domains of T lymphocyte enhancers

Transposable elements (TEs) compose nearly half of mammalian genomes and provide building blocks for cis-regulatory elements. Using high-throughput sequencing, we show that 84 TE subfamilies are overrepresented, and distributed in a lineage-specific fashion in core and boundary domains of CD8(+) T c...

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Detalles Bibliográficos
Autores principales: Ye, Mengliang, Goudot, Christel, Hoyler, Thomas, Lemoine, Benjamin, Amigorena, Sebastian, Zueva, Elina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148579/
https://www.ncbi.nlm.nih.gov/pubmed/32193341
http://dx.doi.org/10.1073/pnas.1912008117