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Alteration of intracellular traffic by monensin; mechanism, specificity and relationship to toxicity

Monensin, a monovalent ion-selective ionophore, facilitates the transmembrane exchange of principally sodium ions for protons. The outer surface of the ionophore-ion comples is composed largely of nonpolar hydrocarbon, which imparts a high solubility to the complexes in nonpolar solvents. In biologi...

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Detalles Bibliográficos
Autores principales: Mollenhauer, Hilton H., James Morré, D., Rowe, Loyd D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Published by Elsevier B.V. 1990
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7148783/
https://www.ncbi.nlm.nih.gov/pubmed/2160275
http://dx.doi.org/10.1016/0304-4157(90)90008-Z