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Ddi1 is a ubiquitin-dependent protease

The Saccharomyces cerevisiae protein Ddi1 and its homologs in higher eukaryotes have been proposed to serve as shuttling factors that deliver ubiquitinated substrates to the proteasome. Although Ddi1 contains both ubiquitin-interacting UBA and proteasome-interacting UBL domains, the UBL domain is at...

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Detalles Bibliográficos
Autores principales: Yip, Matthew C. J., Bodnar, Nicholas O., Rapoport, Tom A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149228/
https://www.ncbi.nlm.nih.gov/pubmed/32193351
http://dx.doi.org/10.1073/pnas.1902298117