Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors

Coronaviruses (CoVs) are positive-sense RNA viruses that can emerge from endemic reservoirs and infect zoonotically, causing significant morbidity and mortality. CoVs encode an endoribonuclease designated EndoU that facilitates evasion of host pattern recognition receptor MDA5, but the target of End...

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Detalles Bibliográficos
Autores principales: Hackbart, Matthew, Deng, Xufang, Baker, Susan C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149396/
https://www.ncbi.nlm.nih.gov/pubmed/32198201
http://dx.doi.org/10.1073/pnas.1921485117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149396/
https://www.ncbi.nlm.nih.gov/pubmed/32198201
http://dx.doi.org/10.1073/pnas.1921485117

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