Cargando…
Coronavirus endoribonuclease targets viral polyuridine sequences to evade activating host sensors
Coronaviruses (CoVs) are positive-sense RNA viruses that can emerge from endemic reservoirs and infect zoonotically, causing significant morbidity and mortality. CoVs encode an endoribonuclease designated EndoU that facilitates evasion of host pattern recognition receptor MDA5, but the target of End...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149396/ https://www.ncbi.nlm.nih.gov/pubmed/32198201 http://dx.doi.org/10.1073/pnas.1921485117 |