15-Epi-LXA(4) and 17-epi-RvD1 restore TLR9-mediated impaired neutrophil phagocytosis and accelerate resolution of lung inflammation

Timely resolution of bacterial infections critically depends on phagocytosis of invading pathogens by polymorphonuclear neutrophil granulocytes (PMNs), followed by PMN apoptosis and efferocytosis. Here we report that bacterial DNA (CpG DNA) and mitochondrial DNA impair phagocytosis and attenuate pha...

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Detalles Bibliográficos
Autores principales: Sekheri, Meriem, El Kebir, Driss, Edner, Natalie, Filep, János G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149425/
https://www.ncbi.nlm.nih.gov/pubmed/32205444
http://dx.doi.org/10.1073/pnas.1920193117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149425/
https://www.ncbi.nlm.nih.gov/pubmed/32205444
http://dx.doi.org/10.1073/pnas.1920193117

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