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Host membrane lipids are trafficked to membranes of intravacuolar bacterium Ehrlichia chaffeensis

Ehrlichia chaffeensis, a cholesterol-rich and cholesterol-dependent obligate intracellular bacterium, partially lacks genes for glycerophospholipid biosynthesis. We found here that E. chaffeensis is dependent on host glycerolipid biosynthesis, as an inhibitor of host long-chain acyl CoA synthetases,...

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Detalles Bibliográficos
Autores principales: Lin, Mingqun, Grandinetti, Giovanna, Hartnell, Lisa M., Bliss, Donald, Subramaniam, Sriram, Rikihisa, Yasuko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149431/
https://www.ncbi.nlm.nih.gov/pubmed/32193339
http://dx.doi.org/10.1073/pnas.1921619117