Cargando…
A combination of two human monoclonal antibodies limits fetal damage by Zika virus in macaques
Human infection by Zika virus (ZIKV) during pregnancy can lead to vertical transmission and fetal aberrations, including microcephaly. Prophylactic administration of antibodies can diminish or prevent ZIKV infection in animal models, but whether passive immunization can protect nonhuman primates and...
Autores principales: | Van Rompay, Koen K. A., Coffey, Lark L., Kapoor, Tania, Gazumyan, Anna, Keesler, Rebekah I., Jurado, Andrea, Peace, Avery, Agudelo, Marianna, Watanabe, Jennifer, Usachenko, Jodie, Singapuri, Anil, Immareddy, Ramya, Ardeshir, Amir, Stuart, Jackson B., Bournazos, Stylianos, Ravetch, Jeffrey V., Balderes, Paul J., Lorenz, Ivo C., Esswein, Shannon R., Keeffe, Jennifer R., Bjorkman, Pamela J., Wang, Qiao, Rice, Charles M., MacDonald, Margaret R., Nussenzweig, Michel C., Robbiani, Davide F. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149495/ https://www.ncbi.nlm.nih.gov/pubmed/32209664 http://dx.doi.org/10.1073/pnas.2000414117 |
Ejemplares similares
-
Evolution of ocular defects in infant macaques following in utero Zika virus infection
por: Yiu, Glenn, et al.
Publicado: (2020) -
A virus-like particle-based bivalent PCSK9 vaccine lowers LDL-cholesterol levels in non-human primates
por: Fowler, Alexandra, et al.
Publicado: (2023) -
Antibody potency, effector function and combinations in protection from SARS-CoV-2 infection in vivo
por: Schäfer, Alexandra, et al.
Publicado: (2020) -
The role of IgG Fc receptors in antibody-dependent enhancement
por: Bournazos, Stylianos, et al.
Publicado: (2020) -
Antibody potency, effector function, and combinations in protection and therapy for SARS-CoV-2 infection in vivo
por: Schäfer, Alexandra, et al.
Publicado: (2020)