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Iron overload contributes to general anaesthesia-induced neurotoxicity and cognitive deficits

BACKGROUND: Increasing evidence suggests that multiple or long-time exposure to general anaesthesia (GA) could be detrimental to cognitive development in young subjects and might also contribute to accelerated neurodegeneration in the elderly. Iron is essential for normal neuronal function, and exce...

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Detalles Bibliográficos
Autores principales: Wu, Jing, Yang, Jian-Jun, Cao, Yan, Li, Huihui, Zhao, Hongting, Yang, Shuofei, Li, Kuanyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149901/
https://www.ncbi.nlm.nih.gov/pubmed/32276637
http://dx.doi.org/10.1186/s12974-020-01777-6