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Oncogenic seRNA functional activation: a novel mechanism of tumorigenesis

seRNA is a noncoding RNA (ncRNA) transcribed from active super-enhancer (SE), through which SE exerts biological functions and participates in various physiological and pathological processes. seRNA recruits cofactor, RNA polymerase II and mediator to constitute and stabilize chromatin loop SE and p...

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Detalles Bibliográficos
Autores principales: Tan, Yuan, Li, Yuejin, Tang, Faqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7149907/
https://www.ncbi.nlm.nih.gov/pubmed/32278350
http://dx.doi.org/10.1186/s12943-020-01195-5