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Targeting Proteasomal Degradation of Soluble, Misfolded Proteins: Ubi Major…

This chapter deals with small molecule modulators of the ubiquitin–proteasome system (UPS). They are designed to restore its impaired capacity to dispose of soluble, dysfunctional protein copies, and to fight its pathological impairment in proteinopathies in general and in tauopathies in particular....

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Detalles Bibliográficos
Autor principal: Seneci, Pierfausto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150093/
http://dx.doi.org/10.1016/B978-0-12-801944-3.00003-5