Rosuvastatin Enhances VSV-G Lentiviral Transduction of NK Cells via Upregulation of the Low-Density Lipoprotein Receptor

Adoptive natural killer (NK) cell therapy is attaining promising clinical outcomes in recent years, but improvements are needed. Genetic modification of NK cells with a tumor antigen-specific receptor on their surface coupled to intracellular signaling domains may lead to enhanced cytotoxicity again...

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Detalles Bibliográficos
Autores principales: Gong, Ying, Klein Wolterink, Roel G.J., Janssen, Ian, Groot, Arjan J., Bos, Gerard M.J., Germeraad, Wilfred T.V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150439/
https://www.ncbi.nlm.nih.gov/pubmed/32300610
http://dx.doi.org/10.1016/j.omtm.2020.03.017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150439/
https://www.ncbi.nlm.nih.gov/pubmed/32300610
http://dx.doi.org/10.1016/j.omtm.2020.03.017

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