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Rosuvastatin Enhances VSV-G Lentiviral Transduction of NK Cells via Upregulation of the Low-Density Lipoprotein Receptor
Adoptive natural killer (NK) cell therapy is attaining promising clinical outcomes in recent years, but improvements are needed. Genetic modification of NK cells with a tumor antigen-specific receptor on their surface coupled to intracellular signaling domains may lead to enhanced cytotoxicity again...
Autores principales: | Gong, Ying, Klein Wolterink, Roel G.J., Janssen, Ian, Groot, Arjan J., Bos, Gerard M.J., Germeraad, Wilfred T.V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150439/ https://www.ncbi.nlm.nih.gov/pubmed/32300610 http://dx.doi.org/10.1016/j.omtm.2020.03.017 |
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