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The M6A methyltransferase METTL3 promotes the development and progression of prostate carcinoma via mediating MYC methylation

N6-methyladenosine (m(6)A) is the richest modification in mammalian messenger RNAs (mRNAs), and exerts key roles in many biological processes, including cancer development, whereas its roles in prostate carcinoma (PCa) remain to be unclear. Here, we found that m(6)A modifications are increased in PC...

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Detalles Bibliográficos
Autores principales: Yuan, Yan, Du, Yang, Wang, Lei, Liu, Xiuheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150444/
https://www.ncbi.nlm.nih.gov/pubmed/32284755
http://dx.doi.org/10.7150/jca.42338