A(2A)R Antagonism with DZD2269 Augments Antitumor Efficacy of Irradiation in Murine Model

Accumulated extracellular adenosine suppresses antitumor immunity via adenosine 2A receptor (A(2A)R). Blockade of A(2A)R with DZD2269 can inhibit phosphorylation of cAMP response element-binding protein mediated by adenosine analogue in vitro and in vivo. Irradiation can cause the release of adenosi...

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Detalles Bibliográficos
Autores principales: Huang, Jiaqi, Zhang, Di, Bai, Yu, Yang, Pamela, Xing, Ligang, Yu, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150468/
https://www.ncbi.nlm.nih.gov/pubmed/32284765
http://dx.doi.org/10.7150/jca.43966

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150468/
https://www.ncbi.nlm.nih.gov/pubmed/32284765
http://dx.doi.org/10.7150/jca.43966

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