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SR9009 induces a REV-ERB dependent anti-small-cell lung cancer effect through inhibition of autophagy
Rationale: The circadian clock coordinates cell proliferation and metabolism and impacts the progression of some diseases, particularly cancer. Pharmacological modulation of the circadian machinery may be an effective therapeutic approach for treating cancer. SR9009 is a specific synthetic agonist o...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150483/ https://www.ncbi.nlm.nih.gov/pubmed/32292508 http://dx.doi.org/10.7150/thno.42478 |