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SR9009 induces a REV-ERB dependent anti-small-cell lung cancer effect through inhibition of autophagy

Rationale: The circadian clock coordinates cell proliferation and metabolism and impacts the progression of some diseases, particularly cancer. Pharmacological modulation of the circadian machinery may be an effective therapeutic approach for treating cancer. SR9009 is a specific synthetic agonist o...

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Detalles Bibliográficos
Autores principales: Shen, Weitao, Zhang, Wei, Ye, Weilin, Wang, Haihong, Zhang, Qingxi, Shen, Jie, Hong, Qingsha, Li, Xiang, Wen, Ge, Wei, Ting, Zhang, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150483/
https://www.ncbi.nlm.nih.gov/pubmed/32292508
http://dx.doi.org/10.7150/thno.42478